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| Cat.No | ACP08166 | Target Name | RNASEK |
|---|---|---|---|
| Target Synonyms | RNASEK; Ribonuclease kappa; RNase K; RNase kappa | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6P5S7 |
|---|
Uniprot Id
Q6P5S7
Target Species
Human
Target Name
RNASEK
Target Full Name
Ribonuclease kappa
Target Function
Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate.; (Microbial infection) Required for the initial stages of clathrin-mediated endocytic uptake of a diverse set of viruses, including dengue, West Nile, Sindbis, Rift Valley Fever, and influenza viruses. Not required for clathrin-mediated endocytosis and macropinocytosis.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
RNase K family
Target Tissue Specificity
Widely expressed.
Target Synonyms
RNASEK; Ribonuclease kappa; RNase K; RNase kappa
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