Recombinant Human Pulmonary surfactant-associated protein D (SFTPD)

Uniprot Id

P35247

Target Species

Human

Target Name

SFTPD

Target Full Name

Pulmonary surfactant-associated protein D

Target Function

Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Target Subcellular Location

Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Target Protein Families

SFTPD family

Target Tissue Specificity

Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).

Target Research Area

Cancer

Target Synonyms

COLEC 7; COLEC7; Collectin-7; Collectin7; Lung surfactant protein D; PSP D; PSP-D; PSP-D Surfactant protein D; PSPD; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein D; Pulmonary surfactant associated protein PSP-D; Pulmonary surfactant-associated protein D; SFTP 4; SFTP4; SFTPD; SFTPD_HUMAN; SP D; SP-D; Surfactant associated protein pulmonary 4; Surfactant protein D; Surfactant pulmonary associated protein D

Target Background

The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism.