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Recombinant Human Nuclear factor erythroid 2-related factor 3 (NFE2L3)

ACP09696

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP09696 Target NameNFE2L3
Target SynonymsNFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2; like 3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-694
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9Y4A8
Background Information
  • Uniprot Id

    Q9Y4A8

  • Target Species

    Human

  • Target Name

    NFE2L3

  • Target Full Name

    Nuclear factor erythroid 2-related factor 3

  • Target Function

    Activates erythroid-specific, globin gene expression.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, CNC subfamily

  • Target Tissue Specificity

    Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.

  • Target Synonyms

    NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2; like 3

  • Target Background

    This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.

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