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| Cat.No | ACP09707 | Target Name | TPRKB |
|---|---|---|---|
| Target Synonyms | CGI 121 ; My019 ; PRPK (p53 related protein kinase) binding protein ; PRPK-binding protein; TP53RK binding protein; TP53RK-binding protein; Tprkb; TPRKB_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-175 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y3C4 |
|---|
Uniprot Id
Q9Y3C4
Target Species
Human
Target Name
TPRKB
Target Full Name
EKC/KEOPS complex subunit TPRKB
Target Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
CGI121/TPRKB family
Target Tissue Specificity
Widely expressed.
Target Synonyms
CGI 121 ; My019 ; PRPK (p53 related protein kinase) binding protein ; PRPK-binding protein; TP53RK binding protein; TP53RK-binding protein; Tprkb; TPRKB_HUMAN
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