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| Cat.No | ACP09818 | Target Name | TBX20 |
|---|---|---|---|
| Target Synonyms | T-box 20; T-box protein 20; T-box transcription factor TBX20; Tbox 20; tbx20; TBX20_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-447 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UMR3 |
|---|
Uniprot Id
Q9UMR3
Target Species
Human
Target Name
TBX20
Target Full Name
T-box transcription factor TBX20
Target Function
Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart.
Target Involvement
Atrial septal defect 4 (ASD4)
Target Subcellular Location
Nucleus.
Target Synonyms
T-box 20; T-box protein 20; T-box transcription factor TBX20; Tbox 20; tbx20; TBX20_HUMAN
Target Background
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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