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Recombinant Human PR domain zinc finger protein 8 (PRDM8)

ACP10285

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Specifications

Cat.No	ACP10285	Target Name	PRDM8
Target Synonyms	PFM5; PR domain containing 8; PR domain containing protein 8; PR domain protein 8; PR domain zinc finger protein 8; PR domain-containing protein 8; PRDM8; PRDM8_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-689
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NQV8

Background Information

Uniprot Id

Q9NQV8
Target Species

Human
Target Name

PRDM8
Target Full Name

PR domain zinc finger protein 8
Target Function

Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival.
Target Involvement

Epilepsy, progressive myoclonic 10 (EPM10)
Target Subcellular Location

Nucleus.
Target Protein Families

Class V-like SAM-binding methyltransferase superfamily
Target Tissue Specificity

Expressed in brain, heart, skeletal muscle, testes, prostate.
Target Research Area

Immunology
Target Synonyms

PFM5; PR domain containing 8; PR domain containing protein 8; PR domain protein 8; PR domain zinc finger protein 8; PR domain-containing protein 8; PRDM8; PRDM8_HUMAN

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Recombinant Human PR domain zinc finger protein 8 (PRDM8)

Specifications

Immunogen Information

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