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| Cat.No | ACP10449 | Target Name | SGIP1 |
|---|---|---|---|
| Target Synonyms | SGIP1; SH3-containing GRB2-like protein 3-interacting protein 1; Endophilin-3-interacting protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BQI5 |
|---|
Uniprot Id
Q9BQI5
Target Species
Human
Target Name
SGIP1
Target Full Name
SH3-containing GRB2-like protein 3-interacting protein 1
Target Function
May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
Target Subcellular Location
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side.
Target Tissue Specificity
Specifically expressed in brain.
Target Synonyms
SGIP1; SH3-containing GRB2-like protein 3-interacting protein 1; Endophilin-3-interacting protein
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