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Recombinant Human HIRA-interacting protein 3 (HIRIP3)

ACP10730

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Specifications

Cat.No	ACP10730	Target Name	HIRIP3
Target Synonyms	HIRA-interacting protein 3; HIRIP3; HIRP3; HIRP3_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-556
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BW71

Background Information

Uniprot Id

Q9BW71
Target Species

Human
Target Name

HIRIP3
Target Full Name

HIRA-interacting protein 3
Target Function

May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.
Target Subcellular Location

Nucleus. Note=Nuclear throughout the cell cycle and is excluded from condensed chromatin during mitosis.
Target Tissue Specificity

Widely expressed. Isoform 1 is predominant in skeletal muscle. Isoform 2 is predominant in liver and heart.
Target Synonyms

HIRA-interacting protein 3; HIRIP3; HIRP3; HIRP3_HUMAN
Target Background

The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Recombinant Human HIRA-interacting protein 3 (HIRIP3)

Specifications

Immunogen Information

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