Recombinant Human Syntaxin-18 (STX18), Truncated

Uniprot Id

Q9P2W9

Target Species

Human

Target Name

STX18

Target Full Name

Syntaxin-18

Target Function

Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein.

Target Protein Families

Syntaxin family

Target Tissue Specificity

Ubiquitous.

Target Synonyms

Cell growth inhibiting gene 9 protein; Cell growth-inhibiting gene 9 protein; DKFZp686O15149; STX18; STX18_HUMAN; Syntaxin-18; Ufe1

Target Background

This gene encodes a member of the syntaxin family of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) which is part of a membrane tethering complex that includes other SNAREs and several peripheral membrane proteins, and is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi complex. The encoded protein is important for the organization of the smooth, rough, and exit site ER subdomains. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants.