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| Cat.No | ACP11290 | Target Name | SEMA6A |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H2E6 |
|---|
Uniprot Id
Q9H2E6
Target Species
Human
Target Name
SEMA6A
Target Full Name
Semaphorin-6A
Target Function
Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.; (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Semaphorin family
Target Synonyms
HT018; SEM6A_HUMAN; SEMA; Sema domain; transmembrane domain (TM); and cytoplasmic domain; (semaphorin) 6A; Sema Q; Sema VIA; SEMA6A 1; Sema6a; SEMA6A-1; SEMA6A1; Semaphorin 6A 1; Semaphorin Q; Semaphorin VIA; Semaphorin-6A; Semaphorin-6A-1; SEMAQ; VIA
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