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Recombinant Human Calmodulin-like protein 5 (CALML5)

ACP11398

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Specifications

Cat.No	ACP11398	Target Name	CALML5
Target Synonyms	CALL5_HUMAN; CALML5; Calmodulin like 5; Calmodulin-like protein 5; Calmodulin-like skin protein; CLSP	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	2-146
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NZT1

Background Information

Uniprot Id

Q9NZT1
Target Species

Human
Target Name

CALML5
Target Full Name

Calmodulin-like protein 5
Target Function

Binds calcium. May be involved in terminal differentiation of keratinocytes.
Target Tissue Specificity

Particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation. Very low expression in lung.
Target Research Area

Cell Biology
Target Synonyms

CALL5_HUMAN; CALML5; Calmodulin like 5; Calmodulin-like protein 5; Calmodulin-like skin protein; CLSP
Target Background

This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.

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Recombinant Human Calmodulin-like protein 5 (CALML5)

Specifications

Immunogen Information

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