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Recombinant Human CDGSH iron-sulfur domain-containing protein 1 (CISD1), Truncated

ACP11700

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11700 Target NameCISD1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NZ45
Background Information
  • Uniprot Id

    Q9NZ45

  • Target Species

    Human

  • Target Name

    CISD1

  • Target Full Name

    CDGSH iron-sulfur domain-containing protein 1

  • Target Function

    Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions.

  • Target Subcellular Location

    Mitochondrion outer membrane; Single-pass type III membrane protein.

  • Target Protein Families

    CISD protein family

  • Target Tissue Specificity

    Expression is reduced in cells derived from cystic fibrosis patients.

  • Target Synonyms

    AU043990; AW743335; C10orf70; CDGSH iron sulfur domain 1; CDGSH iron-sulfur domain-containing protein 1; CISD 1; CISD1; CISD1_HUMAN; D10Ertd214e; MDS029; MGC14684; MitoNEET; RGD1309529; ZCD1; Zinc finger CDGSH type domain 1

  • Target Background

    This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2.

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