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| Cat.No | ACP11773 | Target Name | NT5M |
|---|---|---|---|
| Target Synonyms | 3'-nucleotidase, 3''-nucleotidase; 5''; 5''(3'')-deoxyribonucleotidase; 5'(3')-deoxyribonucleotidase, mitochondrial; 5', mitochondrial; Deoxy-5''-nucleotidase 2; dNT-2; DNT2; mitochondrial; NT5M; NT5M_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 32-228 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NPB1 |
|---|
Uniprot Id
Q9NPB1
Target Species
Human
Target Name
NT5M
Target Full Name
5'(3')-deoxyribonucleotidase, mitochondrial
Target Function
Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
Target Subcellular Location
Mitochondrion.
Target Protein Families
5'(3')-deoxyribonucleotidase family
Target Tissue Specificity
Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.
Target Synonyms
3''-nucleotidase; 5''; 5''(3'')-deoxyribonucleotidase; 5'(3')-deoxyribonucleotidase, mitochondrial; 5',3'-nucleotidase, mitochondrial; Deoxy-5''-nucleotidase 2; dNT-2; DNT2; mitochondrial; NT5M; NT5M_HUMAN
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