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| Cat.No | ACP11884 | Target Name | FAM126A |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-521 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BYI3 |
|---|
Uniprot Id
Q9BYI3
Target Species
Human
Target Name
HYCC1
Target Full Name
Hyccin
Target Function
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P. Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system. May also have a role in the beta-catenin/Lef signaling pathway (Probable).
Target Involvement
Leukodystrophy, hypomyelinating, 5 (HLD5)
Target Subcellular Location
Cytoplasm, cytosol. Cell membrane.
Target Protein Families
FAM126 family
Target Tissue Specificity
Widely expressed. Highest levels in heart, brain, placenta, spleen and testis.
Target Synonyms
Down regulated by Ctnnb1 a; Down regulated by CTNNB1 protein A; Down-regulated by CTNNB1 protein A; DRCTNNB1A; FAM126A; Family with sequence similarity 126 member A; HCC; HLD5; HYCC1; HYCCI_HUMAN; Hyccin; Protein FAM126A
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