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| Cat.No | ACP12705 | Target Name | EDARADD |
|---|---|---|---|
| Target Synonyms | EDARADDEctodysplasin-A receptor-associated adapter protein; EDAR-associated death domain protein; Protein crinkled homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-215 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WWZ3 |
|---|
Uniprot Id
Q8WWZ3
Target Species
Human
Target Name
EDARADD
Target Full Name
Ectodysplasin-A receptor-associated adapter protein
Target Function
Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B.
Target Involvement
Ectodermal dysplasia 11A, hypohidrotic/hair/nail type, autosomal dominant (ECTD11A); Ectodermal dysplasia 11B, hypohidrotic/hair/tooth type, autosomal recessive (ECTD11B)
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis.
Target Synonyms
EDARADDEctodysplasin-A receptor-associated adapter protein; EDAR-associated death domain protein; Protein crinkled homolog
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