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| Cat.No | ACP13361 | Target Name | PHC3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NDX5 |
|---|
Uniprot Id
Q8NDX5
Target Species
Human
Target Name
PHC3
Target Full Name
Polyhomeotic-like protein 3
Target Function
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Target Subcellular Location
Nucleus.
Target Synonyms
Early development regulator 3; Early development regulatory protein 3; EDR3; Homolog of polyhomeotic 3; HPH 3; hPH3; PH3; PHC 3 ; Phc3; PHC3_HUMAN; Polyhomeotic homolog 3 (Drosophila) ; Polyhomeotic homolog 3; Polyhomeotic-like protein 3
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