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Recombinant Human Alstrom syndrome protein 1 (ALMS1), Truncated

ACP13618

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Specifications

Cat.No	ACP13618	Target Name	ALMS1
Target Synonyms	Alms1; ALMS1_HUMAN; ALSS; Alstrom syndrome 1; Alstrom syndrome protein 1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8TCU4

Background Information

Uniprot Id

Q8TCU4
Target Species

Human
Target Name

ALMS1
Target Full Name

Centrosome-associated protein ALMS1
Target Function

Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells.
Target Involvement

Alstrom syndrome (ALMS)
Target Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Associated with centrosomes and basal bodies at the base of primary cilia. Specifically locates to the proximal ends of centrioles and basal bodies. Colocalizes partially with NCAPD2 at these sites. During mitosis localizes to both spindle poles.
Target Tissue Specificity

Expressed in all tissues tested including adipose and pancreas. Expressed by beta-cells of the islets in the pancreas (at protein level).
Target Synonyms

Alms1; ALMS1_HUMAN; ALSS; Alstrom syndrome 1; Alstrom syndrome protein 1

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Recombinant Human Alstrom syndrome protein 1 (ALMS1), Truncated

Specifications

Immunogen Information

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