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| Cat.No | ACP14400 | Target Name | NUDT11 |
|---|---|---|---|
| Target Synonyms | 5''' P1, NUDT11; APS1; DIPP3BDiphosphoinositol polyphosphate phosphohydrolase 3-beta; DIPP-3-beta; DIPP3-beta; hDIPP3beta; EC 3.6.1.52; Diadenosine 5', P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase; AMP-forming); EC 3.6.1.60; Nucleoside diphosphate-linked moiety X motif 11; Nudix motif 11; hAps1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-164 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96G61 |
|---|
Uniprot Id
Q96G61
Target Species
Human
Target Name
NUDT11
Target Full Name
Diphosphoinositol polyphosphate phosphohydrolase 3-beta
Target Function
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Nudix hydrolase family, DIPP subfamily
Target Tissue Specificity
Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is also expressed in pancreas and weakly expressed in thymus, prostate, ovary, lung, small intestine and heart.
Target Synonyms
NUDT11; APS1; DIPP3BDiphosphoinositol polyphosphate phosphohydrolase 3-beta; DIPP-3-beta; DIPP3-beta; hDIPP3beta; EC 3.6.1.52; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase; AMP-forming); EC 3.6.1.60; Nucleoside diphosphate-linked moiety X motif 11; Nudix motif 11; hAps1
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