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| Cat.No | ACP14520 | Target Name | NDNF |
|---|---|---|---|
| Target Synonyms | C4orf31; Fibronectin type III domain containing protein C4orf31; NDNF; NDNF_HUMAN; Neuron-derived neurotrophic factor; PRO6487; Protein NDNF; UNQ2748 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 20-568 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TB73 |
|---|
Uniprot Id
Q8TB73
Target Species
Human
Target Name
NDNF
Target Full Name
Protein NDNF
Target Function
Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed in neurons along the gonadotropin-releasing hormone (GnRH) expressing neurons migratory route.
Target Synonyms
C4orf31; Fibronectin type III domain containing protein C4orf31; NDNF; NDNF_HUMAN; Neuron-derived neurotrophic factor; PRO6487; Protein NDNF; UNQ2748
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