Home Products Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (KCTD13)

Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (KCTD13)

ACP14769

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Specifications

Cat.No	ACP14769	Target Name	KCTD13
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-329	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8WZ19

Background Information

Uniprot Id

Q8WZ19
Target Species

Human
Target Name

KCTD13
Target Full Name

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1
Target Function

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission.
Target Involvement

The gene represented in this entry may act as a disease modifier for autism and schizophrenia associated with recurrent deletions and duplications of chromosome 16p11.2 region (PubMed:22596160, PubMed:25695269).
Target Subcellular Location

Nucleus.
Target Protein Families

BACURD family
Target Tissue Specificity

Expressed in a wide variety of tissues.
Target Synonyms

BACD1_HUMAN; BACURD1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1; BTB/POZ domain-containing protein KCTD13; FKSG86; hBACURD1; KCTD13; PDIP1; POLDIP 1; POLDIP1; Polymerase delta-interacting protein 1; Potassium channel tetramerisation domain containing 13; PP6832; TNFAIP1 like polymerase delta interacting protein 1; TNFAIP1-like protein

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Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (KCTD13)

Specifications

Immunogen Information

Inquire Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (KCTD13) Now

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