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| Cat.No | ACP15176 | Target Name | YAF2 |
|---|---|---|---|
| Target Synonyms | MGC41856; YAF2; YAF2_HUMAN; YY1-associated factor 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-180 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IY57 |
|---|
Uniprot Id
Q8IY57
Target Species
Human
Target Name
YAF2
Target Full Name
YY1-associated factor 2
Target Function
Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
Target Subcellular Location
Nucleus.
Target Synonyms
MGC41856; YAF2; YAF2_HUMAN; YY1-associated factor 2
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