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| Cat.No | ACP15352 | Target Name | SAPCD2 |
|---|---|---|---|
| Target Synonyms | SAPCD2; C9orf140; Suppressor APC domain-containing protein 2; Tumor specificity and mitosis phase-dependent expression protein; TS/MDEP; p42.3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-394 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86UD0 |
|---|
Uniprot Id
Q86UD0
Target Species
Human
Target Name
SAPCD2
Target Full Name
Suppressor APC domain-containing protein 2
Target Function
Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions. Negatively regulates the mitotic apical cortex localization of GPSM2. Involved also in positive regulation of cell proliferation and tumor cell growth.
Target Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, cell cortex. Apical cell membrane. Cell junction, tight junction.
Target Tissue Specificity
Expressed in 5-month-old fetal tissues, including stomach, intestine, colon, liver, brain, lung, heart, spleen and kidney. Undetectable in non-cancerous adult tissues. Expressed in many primary gastric carcinoma, but almost not in adjacent normal mucosa.
Target Synonyms
SAPCD2; C9orf140; Suppressor APC domain-containing protein 2; Tumor specificity and mitosis phase-dependent expression protein; TS/MDEP; p42.3
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