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| Cat.No | ACP15383 | Target Name | NUP54 |
|---|---|---|---|
| Target Synonyms | 54 kDa nucleoporin; MGC13407; Nucleoporin p54; Nup54; NUP54_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-507 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z3B4 |
|---|
Uniprot Id
Q7Z3B4
Target Species
Human
Target Name
NUP54
Target Full Name
Nucleoporin p54
Target Function
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Target Subcellular Location
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
Target Protein Families
NUP54 family
Target Synonyms
54 kDa nucleoporin; MGC13407; Nucleoporin p54; Nup54; NUP54_HUMAN
Target Background
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene.
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