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| Cat.No | ACP15451 | Target Name | TECPR1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z6L1 |
|---|
Uniprot Id
Q7Z6L1
Target Species
Human
Target Name
TECPR1
Target Full Name
Tectonin beta-propeller repeat-containing protein 1
Target Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
Target Subcellular Location
Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
Target Protein Families
TECPR1 family
Target Synonyms
2210010N04Rik; DKFZP434B0335; FLJ23419; FLJ90593; KIAA1358; MGC124730; mKIAA1358; RGD1306873; TCPR1_HUMAN; Tecpr1; tectonin beta propeller repeat containing 1; Tectonin beta-propeller repeat-containing protein 1
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