Recombinant Human Kinectin (KTN1), Truncated

Uniprot Id

Q86UP2

Target Species

Human

Target Name

KTN1

Target Full Name

Kinectin

Target Function

Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin.

Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Vesicle membrane protein anchored to the endoplasmic reticulum.

Target Protein Families

Kinectin family

Target Tissue Specificity

High levels in peripheral blood lymphocytes, testis and ovary, lower levels in spleen, thymus, prostate, small intestine and colon.

Target Synonyms

CG-1 antigen; CG1; CG1 antigen; KIAA0004; Kinectin; Kinesin receptor; Ktn1; KTN1_HUMAN; MU-RMS-40.19

Target Background

This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene.