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| Cat.No | ACP15532 | Target Name | EFL1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z2Z2 |
|---|
Uniprot Id
Q7Z2Z2
Target Species
Human
Target Name
EFL1
Target Full Name
Elongation factor-like GTPase 1
Target Function
Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Target Protein Families
TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family
Target Tissue Specificity
Expressed at low levels in brain. Expression is highly increased in glioma tissues.
Target Synonyms
EFTUD1; Elongation factor like 1; Elongation factor Tu GTP binding domain containing 1; Elongation factor Tu GTP-binding domain-containing protein 1; ETUD1_HUMAN; FAM42A; HsT19294; Protein FAM42A; RIA1; Ribosome assembly 1 homolog
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