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| Cat.No | ACP16187 | Target Name | RUFY4 |
|---|---|---|---|
| Target Synonyms | RUFY4RUN and FYVE domain-containing protein 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-571 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZNE9 |
|---|
Uniprot Id
Q6ZNE9
Target Species
Human
Target Name
RUFY4
Target Full Name
RUN and FYVE domain-containing protein 4
Target Function
Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger.
Target Subcellular Location
Cytoplasmic vesicle, autophagosome.
Target Synonyms
RUFY4RUN and FYVE domain-containing protein 4
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