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| Cat.No | ACP16663 | Target Name | TNS2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q63HR2 |
|---|
Uniprot Id
Q63HR2
Target Species
Human
Target Name
TNS2
Target Full Name
Tensin-2
Target Function
Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin. In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy. Negatively regulates PI3K-AKT pathway activation.
Target Subcellular Location
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Target Tissue Specificity
Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine.
Target Synonyms
C1 domain containing phosphatase and tensin homolog; C1 domain-containing phosphatase and tensin homolog; C1 TEN; C1-TEN; C1TEN; DKFZp686D13244; FLJ16320; KIAA1075; TENC 1; TENC1; TENC1_HUMAN; Tensin 2; Tensin like C1 domain containing phosphatase; Tensin-2; Tensin-like C1 domain-containing phosphatase; TNS2
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