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| Cat.No | ACP16791 | Target Name | PPP2R2D |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-453 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q66LE6 |
|---|
Uniprot Id
Q66LE6
Target Species
Human
Target Name
PPP2R2D
Target Full Name
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Target Function
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Phosphatase 2A regulatory subunit B family
Target Synonyms
2ABD_HUMAN; MDS026; PP2A subunit B isoform B55-delta; PP2A subunit B isoform delta; PP2A subunit B isoform PR55-delta; PP2A subunit B isoform R2-delta; PPP2R2D; Protein phosphatase 2 regulatory subunit B delta; Protein phosphatase 2 regulatory subunit B delta isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
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