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Recombinant Human Ras-interacting protein 1 (RASIP1), Truncated

ACP16871

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16871 Target NameRASIP1
Target SynonymsFLJ20401; Rain; RAIN protein fragment; RAIN_HUMAN; Ras interacting protein 1; Ras-interacting protein 1; RASIP 1; RASIP1; RASIP1 proteinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5U651
Background Information
  • Uniprot Id

    Q5U651

  • Target Species

    Human

  • Target Name

    RASIP1

  • Target Full Name

    Ras-interacting protein 1

  • Target Function

    Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy

  • Target Subcellular Location

    Cytoplasm, perinuclear region. Golgi apparatus, Golgi stack. Note=Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.

  • Target Tissue Specificity

    Highly expressed in heart. Detected at lower levels in placenta and pancreas.

  • Target Synonyms

    FLJ20401; Rain; RAIN protein fragment; RAIN_HUMAN; Ras interacting protein 1; Ras-interacting protein 1; RASIP 1; RASIP1; RASIP1 protein

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