Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 3 (CREB3L3), Truncated

Cat.No	ACP17068	Target Name	CREB3L3
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP17068

Target Name

CREB3L3

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q68CJ9

Background Information

Uniprot Id

Q68CJ9
Target Species

Human
Target Name

CREB3L3
Target Full Name

Cyclic AMP-responsive element-binding protein 3-like protein 3
Target Function

Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE. May function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression. Regulates FGF21 transcription.
Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type II membrane protein.; [Processed cyclic AMP-responsive element-binding protein 3-like protein 3]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Target Protein Families

BZIP family, ATF subfamily
Target Tissue Specificity

Exclusively expressed in liver. Underexpressed in hepatocellular carcinoma tissues.
Target Synonyms

CREB3L3; CREBH; HYST1481Cyclic AMP-responsive element-binding protein 3-like protein 3; cAMP-responsive element-binding protein 3-like protein 3; Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3]
Target Background

This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants.

Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 3 (CREB3L3), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 3 (CREB3L3), Truncated Now

Related Products