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| Cat.No | ACP17326 | Target Name | DOCK11 |
|---|---|---|---|
| Target Synonyms | ACG; Activated Cdc42-associated guanine nucleotide exchange factor; Dedicator of cytokinesis protein 11; DOC11_HUMAN; Dock11; ZIZ2; Zizimin-2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5JSL3 |
|---|
Uniprot Id
Q5JSL3
Target Species
Human
Target Name
DOCK11
Target Full Name
Dedicator of cytokinesis protein 11
Target Function
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42.
Target Protein Families
DOCK family
Target Synonyms
ACG; Activated Cdc42-associated guanine nucleotide exchange factor; Dedicator of cytokinesis protein 11; DOC11_HUMAN; Dock11; ZIZ2; Zizimin-2
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