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| Cat.No | ACP17640 | Target Name | LRRC26 |
|---|---|---|---|
| Target Synonyms | LRRC26; CAPC; Leucine-rich repeat-containing protein 26; BK channel auxiliary gamma subunit LRRC26; Cytokeratin-associated protein in cancer | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q2I0M4 |
|---|
Uniprot Id
Q2I0M4
Target Species
Human
Target Name
LRRC26
Target Full Name
Leucine-rich repeat-containing protein 26
Target Function
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton.
Target Tissue Specificity
Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon
Target Synonyms
LRRC26; CAPC; Leucine-rich repeat-containing protein 26; BK channel auxiliary gamma subunit LRRC26; Cytokeratin-associated protein in cancer
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