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| Cat.No | ACP18083 | Target Name | STX5 |
|---|---|---|---|
| Target Synonyms | OTTHUMP00000185028; SED5; STX5; STX5_HUMAN; STX5A; Syntaxin 5; Syntaxin 5A; Syntaxin-5; Syntaxin5; Syntaxin5A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13190 |
|---|
Uniprot Id
Q13190
Target Species
Human
Target Name
STX5
Target Full Name
Syntaxin-5
Target Function
Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus.
Target Subcellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein. Golgi apparatus membrane.
Target Protein Families
Syntaxin family
Target Synonyms
OTTHUMP00000185028; SED5; STX5; STX5_HUMAN; STX5A; Syntaxin 5; Syntaxin 5A; Syntaxin-5; Syntaxin5; Syntaxin5A
Target Background
This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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