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Recombinant Human ETS-related transcription factor Elf-2 (ELF2)

ACP18221

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18221 Target NameELF2
Target SynonymsELF2; NERFETS-related transcription factor Elf-2; E74-like factor 2; New ETS-related factorFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-593
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ15723
Background Information
  • Uniprot Id

    Q15723

  • Target Species

    Human

  • Target Name

    ELF2

  • Target Full Name

    ETS-related transcription factor Elf-2

  • Target Function

    Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.; Isoform 2 may function in repression of RUNX1-mediated transactivation.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ETS family

  • Target Tissue Specificity

    Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung,

  • Target Synonyms

    ELF2; NERFETS-related transcription factor Elf-2; E74-like factor 2; New ETS-related factor

  • Target Background

    Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Located in cytosol and nuclear body.

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