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| Cat.No | ACP18248 | Target Name | GANAB |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14697 |
|---|
Uniprot Id
Q14697
Target Species
Human
Target Name
GANAB
Target Full Name
Neutral alpha-glucosidase AB
Target Function
Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia.
Target Involvement
Polycystic kidney disease 3 (PKD3)
Target Subcellular Location
Endoplasmic reticulum. Golgi apparatus. Melanosome.
Target Protein Families
Glycosyl hydrolase 31 family
Target Tissue Specificity
Detected in placenta. Isoform 1 and isoform 2 are expressed in the kidney and liver.
Target Synonyms
Alpha glucosidase II alpha subunit; Alpha-glucosidase 2; G2AN; GANAB; GANAB_HUMAN; Glu II; Glucosidase alpha neutral AB; Glucosidase II alpha; Glucosidase II subunit alpha; GluII; KIAA0088; Neutral alpha glucosidase AB; Neutral alpha glucosidase AB precursor ; Neutral alpha-glucosidase AB
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