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| Cat.No | ACP18259 | Target Name | DOC2A |
|---|---|---|---|
| Target Synonyms | DOC2ADouble C2-like domain-containing protein alpha; Doc2; Doc2-alpha | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-400 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14183 |
|---|
Uniprot Id
Q14183
Target Species
Human
Target Name
DOC2A
Target Full Name
Double C2-like domain-containing protein alpha
Target Function
Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
Target Subcellular Location
Lysosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome.
Target Tissue Specificity
Predominantly expressed in brain. Also expressed in testis.
Target Synonyms
DOC2ADouble C2-like domain-containing protein alpha; Doc2; Doc2-alpha
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