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| Cat.No | ACP18775 | Target Name | ECSCR |
|---|---|---|---|
| Target Synonyms | ECSCR; ECSCR_HUMAN; Endothelial cell-specific chemotaxis regulator; Endothelial cell-specific molecule 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q19T08 |
|---|
Uniprot Id
Q19T08
Target Species
Human
Target Name
ECSCR
Target Full Name
Endothelial cell-specific chemotaxis regulator
Target Function
Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Target Protein Families
ECSCR family
Target Tissue Specificity
Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells.
Target Synonyms
ECSCR; ECSCR_HUMAN; Endothelial cell-specific chemotaxis regulator; Endothelial cell-specific molecule 2
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