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| Cat.No | ACP18830 | Target Name | IRS2 |
|---|---|---|---|
| Target Synonyms | Insulin receptor substrate 2; IRS 2; IRS-2; Irs2; IRS2_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y4H2 |
|---|
Uniprot Id
Q9Y4H2
Target Species
Human
Target Name
IRS2
Target Full Name
Insulin receptor substrate 2
Target Function
May mediate the control of various cellular processes by insulin.
Target Subcellular Location
Cytoplasm, cytosol.
Target Synonyms
Insulin receptor substrate 2; IRS 2; IRS-2; Irs2; IRS2_HUMAN
Target Background
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
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