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| Cat.No | ACP19018 | Target Name | HRASLS2 |
|---|---|---|---|
| Target Synonyms | PLAAT2; HRASLS2; Phospholipase A and acyltransferase 2; EC 2.3.1.-; EC 3.1.1.32; EC 3.1.1.4; HRAS-like suppressor 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NWW9 |
|---|
Uniprot Id
Q9NWW9
Target Species
Human
Target Name
PLAAT2
Target Full Name
Phospholipase A and acyltransferase 2
Target Function
Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor. Exhibits high phospholipase A1/2 activity and low N-acyltransferase activity.
Target Subcellular Location
Cytoplasm. Membrane; Single-pass membrane protein.
Target Protein Families
H-rev107 family
Target Tissue Specificity
Expressed in liver, kidney, small intestine testis and colon. Undetectable in testis, placenta, salivary gland and fetal brain.
Target Synonyms
PLAAT2; HRASLS2; Phospholipase A and acyltransferase 2; EC 2.3.1.-; EC 3.1.1.32; EC 3.1.1.4; HRAS-like suppressor 2
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