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| Cat.No | ACP19713 | Target Name | MOCS2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-88 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O96033 |
|---|
Uniprot Id
O96033
Target Species
Human
Target Name
MOCS2
Target Full Name
Molybdopterin synthase sulfur carrier subunit
Target Function
Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
Target Involvement
Molybdenum cofactor deficiency, complementation group B (MOCODB)
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
MoaD family, MOCS2A subfamily
Target Tissue Specificity
Widely expressed. Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes.
Target Synonyms
MOCS2; MOCO1; Molybdopterin synthase sulfur carrier subunit; MOCO1-A; Molybdenum cofactor synthesis protein 2 small subunit; Molybdenum cofactor synthesis protein 2A; MOCS2A; Molybdopterin-synthase small subunit; Sulfur carrier protein MOCS2A
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