Home Products Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3′,5′-cyclic phosphodiesterase 8B (PDE8B), Truncated

Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3′,5′-cyclic phosphodiesterase 8B (PDE8B), Truncated

ACP19715

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Specifications

Cat.No	ACP19715	Target Name	PDE8B
Target Synonyms	5'-cyclic phosphodiesterase 8B; HSPDE 8B; HsPDE8B; PDE 8B; PDE8B; PDE8B_HUMAN; Phosphodiesterase 8B; Phosphodiesterase8B; PIG22	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O95263

Background Information

Uniprot Id

O95263
Target Species

Human
Target Name

PDE8B
Target Full Name

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
Target Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland.
Target Involvement

Striatal degeneration, autosomal dominant 1 (ADSD1); Primary pigmented nodular adrenocortical disease 3 (PPNAD3)
Target Protein Families

Cyclic nucleotide phosphodiesterase family, PDE8 subfamily
Target Tissue Specificity

Abundantly expressed in the thyroid. Also very weakly expressed in brain, spinal cord and placenta. In the thyroid isoform 1 predominates, and isoforms 2 and 6 are also highly expressed. In the placenta isoforms 1 and 2 are expressed equally. In the brain
Target Synonyms

3' 5' cyclic nucleotide phosphodiesterase 8B; 3'5' cyclic nucleotide phosphodiesterase 8B ; Cell proliferation-inducing gene 22 protein; FLJ11212; High affinity cAMP specific and IBMX insensitive 3' 5' cyclic phosphodiesterase 8B; High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8B; High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; HSPDE 8B; HsPDE8B; PDE 8B; PDE8B; PDE8B_HUMAN; Phosphodiesterase 8B; Phosphodiesterase8B; PIG22

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Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3′,5′-cyclic phosphodiesterase 8B (PDE8B), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3′,5′-cyclic phosphodiesterase 8B (PDE8B), Truncated Now

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