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| Cat.No | ACP20051 | Target Name | HPR |
|---|---|---|---|
| Target Synonyms | A-259H10.2; Haptoglobin related locus; haptoglobin related protein; Haptoglobin-related protein; HP; hpr; HPTR_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 20-348 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P00739 |
|---|
Uniprot Id
P00739
Target Species
Human
Target Name
HPR
Target Full Name
Haptoglobin-related protein
Target Function
Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase S1 family
Target Tissue Specificity
In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell
Target Synonyms
A-259H10.2; Haptoglobin related locus; haptoglobin related protein; Haptoglobin-related protein; HP; hpr; HPTR_HUMAN
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