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Recombinant Human Proteasome assembly chaperone 1 (PSMG1)

ACP20500

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Specifications

Cat.No	ACP20500	Target Name	PSMG1
Target Synonyms	PSMG1; C21LRP; DSCR2; PAC1; Proteasome assembly chaperone 1; PAC-1; Chromosome 21 leucine-rich protein; C21-LRP; Down syndrome critical region protein 2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	2-288
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O95456

Background Information

Uniprot Id

O95456
Target Species

Human
Target Name

PSMG1
Target Full Name

Proteasome assembly chaperone 1
Target Function

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
Target Subcellular Location

Cytoplasm. Endoplasmic reticulum.
Target Protein Families

PSMG1 family
Target Tissue Specificity

In the adult, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines.
Target Synonyms

PSMG1; C21LRP; DSCR2; PAC1; Proteasome assembly chaperone 1; PAC-1; Chromosome 21 leucine-rich protein; C21-LRP; Down syndrome critical region protein 2
Target Background

Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and nucleoplasm. Part of chaperone complex.

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Recombinant Human Proteasome assembly chaperone 1 (PSMG1)

Specifications

Immunogen Information

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