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| Cat.No | ACP20745 | Target Name | COBL |
|---|---|---|---|
| Target Synonyms | cobL; COBL_HUMAN; DKFZp686G13227; KIAA0633; MGC131893; Protein cordon-bleu | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75128 |
|---|
Uniprot Id
O75128
Target Species
Human
Target Name
COBL
Target Full Name
Protein cordon-bleu
Target Function
Plays an important role in the reorganization of the actin cytoskeleton. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells. Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles.
Target Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, ruffle. Cytoplasm.
Target Synonyms
cobL; COBL_HUMAN; DKFZp686G13227; KIAA0633; MGC131893; Protein cordon-bleu
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