Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP20756 | Target Name | HPGDS |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-199 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60760 |
|---|
Uniprot Id
O60760
Target Species
Human
Target Name
HPGDS
Target Full Name
Hematopoietic prostaglandin D synthase
Target Function
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
Target Subcellular Location
Cytoplasm.
Target Protein Families
GST superfamily, Sigma family
Target Tissue Specificity
Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
Target Synonyms
Cerebrin 28; Glutathione dependent PGD synthetase; Glutathione S-transferase; Glutathione-dependent PGD synthase; Glutathione-requiring prostaglandin D synthase; GST class-sigma; H PGDS; H-PGDS; Haematopoietic prostaglandin D synthase; Haematopoietic prostaglandin D2 synthase; Hematopoietic prostaglandin D synthase; Hpgds; HPGDS_HUMAN; Prostaglandin D synthase; Prostaglandin D2 synthase hematopoietic; Prostaglandin H2 D isomerase; Prostaglandin-H2 D-isomerase; PTGDS2
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
