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Recombinant Human Prickle-like protein 3 (PRICKLE3)

ACP20773

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Specifications

Cat.No	ACP20773	Target Name	PRICKLE3
Target Synonyms	PRICKLE3; LMO6Prickle planar cell polarity protein 3; LIM domain only protein 6; LMO-6; Prickle-like protein 3; Pk3; Triple LIM domain protein 6	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-615
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O43900

Background Information

Uniprot Id

O43900
Target Species

Human
Target Name

PRICKLE3
Target Full Name

Prickle planar cell polarity protein 3
Target Function

Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation. PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module. Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions. Involved in the organization of the basal body. Involved in cilia growth and positioning. Required for proper assembly, stability, and function of mitochondrial membrane ATP synthase (mitochondrial complex V).
Target Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion.
Target Protein Families

Prickle / espinas / testin family
Target Tissue Specificity

Widely expressed.
Target Synonyms

PRICKLE3; LMO6Prickle planar cell polarity protein 3; LIM domain only protein 6; LMO-6; Prickle-like protein 3; Pk3; Triple LIM domain protein 6

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Recombinant Human Prickle-like protein 3 (PRICKLE3)

Specifications

Immunogen Information

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