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Recombinant Human Pre-mRNA-processing factor 6 (PRPF6), Truncated

ACP20847

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Specifications

Cat.No	ACP20847	Target Name	PRPF6
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O94906

Background Information

Uniprot Id

O94906
Target Species

Human
Target Name

PRPF6
Target Full Name

Pre-mRNA-processing factor 6
Target Function

Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
Target Involvement

Retinitis pigmentosa 60 (RP60)
Target Subcellular Location

Nucleus, nucleoplasm. Nucleus speckle.
Target Tissue Specificity

Widely expressed.
Target Synonyms

Androgen receptor N terminal domain transactivating protein 1; ANT 1; ANT1; C20orf14; hPrp6; p102 U5 small nuclear ribonucleoprotein particle binding protein; pre-mRNA processing factor 6; Pre-mRNA-processing factor 6; PRP6 homolog; PRP6 pre mRNA processing factor 6 homolog; PRP6_HUMAN; PRPF6; Putative mitochondrial outer membrane protein import receptor; TOM; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein; U5-102K
Target Background

The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.

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Recombinant Human Pre-mRNA-processing factor 6 (PRPF6), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Pre-mRNA-processing factor 6 (PRPF6), Truncated Now

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