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Recombinant Human Nebulette (NEBL), Truncated

ACP20862

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20862 Target NameNEBL
Target SynonymsNEBL; LNEBLNebulette; Actin-binding Z-disk proteinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO76041
Background Information
  • Uniprot Id

    O76041

  • Target Species

    Human

  • Target Name

    NEBL

  • Target Full Name

    Nebulette

  • Target Function

    Binds to actin and plays an important role in the assembly of the Z-disk. May functionally link sarcomeric actin to the desmin intermediate filaments in the heart muscle sarcomeres. Isoform 2 might play a role in the assembly of focal adhesion.

  • Target Subcellular Location

    [Isoform 2]: Cytoplasm.

  • Target Tissue Specificity

    Abundantly expressed in cardiac muscle, but not in skeletal or smooth muscle. Localized to Z-lines in cardiac cells and to dense bodies in nonmuscle cells. Isoform 2 is expressed in non-muscle cells such as in fibroblasts.

  • Target Synonyms

    NEBL; LNEBLNebulette; Actin-binding Z-disk protein

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