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| Cat.No | ACP21002 | Target Name | SEC24A |
|---|---|---|---|
| Target Synonyms | SEC24A; Protein transport protein Sec24A; SEC24-related protein A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95486 |
|---|
Uniprot Id
O95486
Target Species
Human
Target Name
SEC24A
Target Full Name
Protein transport protein Sec24A
Target Function
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
Target Subcellular Location
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
Target Protein Families
SEC23/SEC24 family, SEC24 subfamily
Target Synonyms
SEC24A; Protein transport protein Sec24A; SEC24-related protein A
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